Wednesday, March 31, 2010

Henrietta Lacks' story opens minds

Laura Mariani, a graduate student in neuroscience, helped arrange the recent Emory visit of author Rebecca Skloot, whose new book tells the human story behind the HeLa cell line. Mariani wrote about Skloot's visit on her blog, "Neurotypical?"

Following is an exerpt from her posting:

"As a scientist, I've known about HeLa for a long time, and I was even told a brief version of the Henrietta Lacks story in my college biology lab, but I'd never felt personally connected to this chapter of scientific history. Reading "The Immortal Life of Henrietta Lacks" made me imagine how I'd feel if I learned that part of my father, who died of cancer when I was 17, was alive in a lab somewhere. It made me look up the origins of other immortalized cell lines that I have used, like SH-SY5Y cells. (Those cells were derived from a bone marrow sample from an anonymous four-year-old girl with metastatic neuroblastoma -- "After progressive debilitation and continued growth of tumor, the patient died in January 1971.") It made me re-evaluate every sarcastic conversation I've had with my fellow grad students about our required ethics training seminars. (Suggestion to ethics seminar organizers: Put this book on the syllabus.)"

Read the full account of Skloot's visit on Mariani's blog.

Monday, March 29, 2010

Going off the grid for spring break


Photo by Spencer Ramsey

From Emory Report:

“I want them to deal with the flies. I want them to understand the beginnings of medicine. I want them to experience an authentic Amazonian, shamanistic culture,” says Oxford College sociologist Mike McQuaide, explaining why he takes students into a remote village in Ecuador every spring break.

Students in his course Social Change in Developing Societies study sociology, psychology and anthropology in the classroom before heading to the field – the village of Rio Blanco, situated in the upper Amazon basin. The group flies to Quito, then travels by bus to Napo province, where they switch to small boats on the Napo River. The final leg of the journey is a three-hour hike through jungle.

In the village, the students stay with the local people, who are known as Quichua. The students sleep on the same rough-hewn beds, eat the same foods and see the daily life of the locals.

Photo by Michael Dale

“In Rio Blanco, they’re off the grid,” McQuaide says. “Most of them have never experienced that.”

No Internet. No electricity. No phones – although that’s starting to change during the years that McQuaide has been visiting the region.

Watch a video interview with McQuaide on cell phones and globalization:


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Thursday, March 25, 2010

The East-meets-West experiment


Tibetan prayer flags join the U.S. flag on the Quad during Tibet Week.

Word is spreading about the success of the Emory-Tibet Science Initiative, said Geshe Lhakdor, director of the Library of Tibetan Works and Archives, who is on campus for Tibet Week. “Now, when I travel around the world, people ask me about this initiative at Emory, and whether they can start something similar at their universities."

The program to bring the knowledge of Buddhist meditative and traditional healing practices to Westerners, and the knowledge of modern science to Tibetan monastics, is now in its third year.

As Geshe Lhakdor explained: “Spiritual traditions, like Buddhism, help us to cultivate a proper perspective and mental outlook. If you don’t have that, your problems can’t be solved through technology. We need both science and spirituality. That is extremely clear. We must walk together, share our knowledge, and help each other.”

The Emory-Tibet Partnership has inspired several innovative projects. A study abroad program in Dharamsala, India, immerses Emory students in Tibetan mind-body sciences. The Emory Mind-Body Program is investigating the mental health benefits of meditation. Emory biochemist Raymond Schinazi is heading a project to analyze Tibetan medical compounds for anti-viral and anti-cancer properties.

His Holiness the XIV Dalai Lama plans to return to Emory Oct. 17-19 for a series of public talks, in his role as Emory’s Presidential Distinguished Professor.

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Wednesday, March 24, 2010

How we learn language


From the Quadrangle magazine:

“Humans have evolved with some general capacities to do things like remember, pay attention, recognize patterns,” says psychologist Laura Namy, who heads the Language and Learning Lab at Emory’s Child Study Center.

"Pattern recognition, for example, can help you see a tiger in the grass, which would have helped early humans, but that same cognitive capacity can lend itself to lots of other skills, including the trick of discovering how language works."

Early on, children use gestures spontaneously, Namy says. "They might make one hand motion for ‘more,’ another for ‘juice,’ or ‘up.’ Then as verbal vocabulary develops, the gestures sort of fall by the wayside. While it’s not anything we teach our kids, we want to learn what parents do to encourage this, either with their own gestures or by their responses.”



Our sensitivity to tone of voice is remarkable, too. “When we stress words in certain ways, for instance by saying ‘eNORmous’ or ‘teeny-weeny,’ we’re doing with our voice what we would call an iconic gesture with our hands. And kids get that,” Namy says. “Even with made-up words, pre-schoolers can reliably infer from these cues whether a word should mean big or small, hot or cold. We can even filter speech so that content is gone and all that’s left is tone of voice. And even then, people can guess.”

Sound symbolism goes further. In English, for example, sl words often refer to slippery or slimy things, and sn words to nasal things (think sniffle and snort). “And while that’s not true for all words in every language, there is something about certain sound clusters that makes them common carriers of meaning across languages,” Namy says. “If you play an Urdu word to native English speakers who’ve never heard Urdu and ask them to say if it means tall or short, they guess right more often than chance would allow.”

Emory recently brought together leading scholars in the emerging field of sound symbolism for a conference: “Sound Symbolism: Challenging the Arbitrariness of Language.”

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Tuesday, March 23, 2010

Are labs creating mad scientists?

Photo by David Zeiger from Theater Emory's "Frankenstein."

“It seems scientists could use some religion, or at least some soul, or at least a moral compass to orientate themselves through the increasingly blurry lines that sketch out the day-to-day ethics of our labs and clinics,” writes biologist Arri Eisen in Religion Dispatches.

An excerpt from the article:

Army researcher Bruce Ivins commits suicide as the FBI closes in on him as a top suspect in the US anthrax mail deaths; University of Alabama biology professor Amy Bishop guns down her colleagues in a faculty meeting; top climate scientists’ hacked e-mail reveals childish bickering and apparent suppression of research that goes against global warming; Nobel-winning UN scientist Rajendra Pachauri accused of serious financial conflicts of interest; top university psychiatrists under Senate investigation for not disclosing significant cash payments from pharmaceutical companies whose drugs they are also researching.

Good Lord! Seems like hardly a week’s gone by lately without some new revelation about scientists gone mad or bad or both. What’s up?

First, top research scientists work in very intense environments that often ignore, or worse, reward narcissistic behaviors. In my quarter-century in science, I’ve seen many social behaviors (barely on the edge of what would normally be accepted) excused as long as those involved were bringing in a lot of money and prestige and publishing a lot of papers.


Second, and to add spice and challenge to this intense environment, the US Senate passed the Bayh-Dole Act in 1980. For the first time, universities and their researchers could financially benefit from their research and innovations. This is good, the reasoning went, because we not only want to keep our best minds in universities, but we also want scientists to reap the benefits of their own ideas. Of course, when big bucks are at stake humans have a tendency to behave badly and change priorities.

Read the full article.

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