Monday, February 11, 2019

Atlanta Science Festival to launch at Emory with the power of WOW!

Wow in the World host Mindy Thomas, center, will kick off the Atlanta Science Festival with the help of musical duo The Pop Ups (Jacob Stein, left, and Jason Rabinowitz).

By Carol Clark

Watch for serious fun to spring up all around town as part of the 2019 Atlanta Science Festival, March 9 to March 23. The festival begins with a Wow in the World Pop Up Party on Saturday, March 9 from 11 am to noon on the Emory University campus. Mindy Thomas, a host of the popular NPR science-themed podcast Wow in the World, will engage curious kids and their grown-ups in games and skits with mad musical accompaniment by the Pop Ups — creators of the children’s music album Giants of Science.

A "Wow in the World" launch
“Wow in the World is an excellent program for kids and we really wanted to bring the energy of its team to Atlanta,” says Meisa Salaita, co-director of the Atlanta Science Festival. “They tie new and relevant research into interesting topics for kids, everything from ants that explode to seaweed that might boost your brain power. Kids are our future and getting them excited about science is so important.”

Kids will enjoy skits and games inspired by topics from the podcast like “Contagion Alert: The Science of Trying Not to Laugh” and “It SNOT What You Think.” Tickets are required for the launch event, set at Emory’s Glenn Memorial United Methodist Church, and it is expected to sell out.

The Atlanta Science Festival, or ASF, will feature more than 100 events throughout the metro area hosted by school districts, universities, museums, businesses and civic and community groups. Delta Air Lines is the presenting sponsor for 2019.

This year, Emory scientists will lead a walk with Mesozoic dinosaurs, discuss how neuro-engineering is blurring the lines between mind and machine and describe the physics of how babies learn to talk. Click here to see a full list of events connected to Emory.

Hundreds of visitors are expected on the Emory campus on Friday, March 22 for the perennial festival favorites, "Chemistry Carnival" and "Physics Live!"

“Science on Stage: The Forgotten Organ,” stars the bacteria, fungi and viruses within the human microbiome that shapes every one of us from birth. The Emory Center for the Study of Human Health teamed up with Theater at Emory to have playwrights quickly produce short plays about the microbiome. The playwrights drew their inspiration from a New York Times bestselling book by acclaimed science writer Ed Yong, “I Contain Multitudes: The Microbes Within Us and a Grander View of Life.”

Yong will join the playwrights for readings of their works and a panel discussion of this unique collaboration between art and science. This event is set for Wednesday, March 20, at 6:30 pm at the Carter Presidential Library and Museum.

The Emory event “Become an Archaeologist” returns on Thursday, March 21 from 6 to 8 pm. This year the faculty and students involved are taking their bones off campus, to Brownwood Park in East Atlanta Village. The Emory experts will teach community members how to extract DNA and put pieces of ancient objects back together like a puzzle. “It’s a great example of the festival taking events that we know are popular and setting them in other parts of the city so that we can continue to reach new audiences and connect in different ways,” Salaita says. “Our goal is to keep broadening access to our programming.”

Two perennial festival favorites — Chemistry Carnival and Physics Live! — return this year to the Emory campus on Friday, March 22 from 3:30 to 7 pm. Emory science faculty and students will explain their research, give lab tours, and entertain with games like Peptide Jenga, a chance to play with giant soap bubbles and tastings of liquid nitrogen ice cream. Hundreds of visitors are expected to turn out for the events, held in the Mathematics and Science Center and Atwood Chemistry Center.

Oxford hosts "Ada and the Engine"
A highlight on Emory’s Oxford campus will be performances of the play “Ada and the Engine,” portraying the groundbreaking career of Ada Lovelace — a mathematician, poet and the first computer programmer. During the festival, the play will be performed Friday and Saturday, March 21 and 22, at 7:30 pm. Performances will be followed by talks on the themes of women working in a field dominated by men, and a chance to walk through a multimedia gallery of women in STEM fields from throughout history.

The festival culminates on Saturday, March 23 with the Exploration Expo at Piedmont Park — a day-long, free carnival of science with hundreds of hands-on activities. More than a dozen booths will feature Emory faculty and students, who will engage crowds in activities with names like “Air Pollution Particle Toss,” “Opening a Can of Worms: Exploring Biomaterials and Nanotechnology with Alginate Gummy Worms,” “Smell the World,” and “Can You Guess What Your Brain is Thinking?”

Founded in 2014 by Emory University, Georgia Tech and the Metro Atlanta Chamber, the ASF celebration of local science, technology, engineering and math has brought programming to more than 200,000 people in the metro region, reaching a diverse audience of a wide variety of ages. 

Special funding from sponsors such as Delta, the Arthur M. Blank Family Foundation and others is helping ASF soar to new heights and extend some of its programming and events year-round. A chief science officer program charges student representatives from middle schools and high school to foster science communities at their schools.

“These chief science officers, who are elected by their student bodies, receive leadership training, meet with state legislators and learn about the role of science and policy,” Salaita says. “We launched the program this year with 22 students and we plan to grow exponentially over the next three years to 200 students.”

Another program piloted this past year by the ASF is a science communication training fellowship for graduate students and post-doctoral fellows. “We’ve started with eight students who met monthly to learn about narrative in science communication, data visualization and other communication techniques,” Salaita says. “They will use their new skills to create events for the science festival and give informal talks to the general public.”

Another new component of the ASF is a year-round calendar of STEM-themed activities. “We want people to stay connected to science,” Salaita explains. “Our new events calendar is a guide for family friendly activities in the metro Atlanta area when the festival’s not happening.”

Tuesday, February 5, 2019

A new spin on computing: Chemist leads $3.9 million DOE quest for quantum software

"Quantum computers are not just exponentially faster, they work in a radically different way from classical computers," says chemist Francesco Evangelista, who is leading a project to develop quantum software.

By Carol Clark

When most people think of a chemistry lab, they picture scientists in white coats mixing chemicals in beakers. But the lab of theoretical chemist Francesco Evangelista looks more like the office of a tech start-up. Graduate students in jeans and t-shirts sit around a large, round table chatting as they work on laptops.

“A ‘classical’ chemist is focused on getting a chemical reaction and creating new molecules,” explains Evangelista, assistant professor at Emory University. “As theoretical chemists, we want to understand how chemistry really works — how all the atoms involved interact with one another during a reaction.”

Working at the intersection of math, physics, chemistry and computer science, the theorists develop algorithms to serve as simulation models for the molecular behaviors of atomic nuclei and electrons. They also develop software that enables them to feed these algorithms into “super” computers — nearly a million times faster than a laptop — to study chemical processes.

The problem is, even super computers are taxed by the mind-boggling combinatorial complexity underlying reactions. That limits the pace of the research.

“Computers have hit a barrier in terms of speed,” Evangelista says. “One way to make them more powerful is to make transistors smaller, but you can’t make them smaller than the width of a couple of atoms — the limit imposed by quantum mechanics. That’s why there is a race right now to make breakthroughs in quantum computing.”

Evangelista and his graduate students have now joined that race.

The Department of Energy (DOE) awarded Evangelista $3.9 million to lead research into the development of software to run the first generation of quantum computers. He is the principal investigator for the project, encompassing scientists at seven universities, to develop new methods and algorithms for calculating problems in quantum chemistry. The tools the team develops will be open access, made available to other researchers for free.

Watch a video about Francesco Evangelista's work, 
produced by the Camille & Henry Dreyfus Foundation:


While big-data leaders — such as IBM, Google, Intel and Rigetti — have developed prototypes of quantum computers, the field remains in its infancy. Many technological challenges remain before quantum computers can fulfill their promise of speeding up calculations to crack major mysteries of the natural world.

The federal government will play a strong supporting role in achieving this goal. President Trump recently signed a $1.2 billion law, the National Quantum Initiative Act, to fund advances in quantum technologies over the next five years.

“Right now, it’s a bit of a wild west, but eventually people working on this giant endeavor are going to work out some of the current technological problems,” Evangelista says. “When that happens, we need to have quantum software ready and a community trained to use it for theoretical chemistry. Our project is working on programming codes that will someday get quantum computers to do the calculations we want them to do.”

The project will pave the way for quantum computers to simulate chemical systems critical to the mission of the DOE, such as transition metal catalysts, high-temperature superconductors and novel materials that are beyond the realm of simulation on “classical” computers. The insights gained could speed up research into how to improve everything from solar power to nuclear energy.

Unlike objects in the “classical” world, that we can touch, see and experience around us, nature behaves much differently in the ultra-small quantum world of atoms and subatomic particles.

“One of the weird things about quantum mechanics is that you can’t say whether an electron is actually only here or there,” Evangelista says.

He takes a coin from his pocket. “In the classical world, we know that an object like this quarter is either in my pocket or in your pocket,” Evangelista says. “But if this was an electron, it could be in both our pockets. I cannot tell you exactly where it is, but I can use a wave function to describe the likelihood of whether it is here or there.”

To make things even more complicated, the behavior of electrons can be correlated, or entangled. When objects in our day-to-day lives, like strands of hair, become entangled they can be teased apart and separated again. That rule doesn’t apply at the quantum scale where entangled objects are somehow intimately connected even if they are apart in space.

“Three electrons moving in three separate orbitals can actually be interacting with one another,” Evangelista says. “Somehow they are talking together and their motion is correlated like ballerinas dancing and moving in a concerted way.”

Graduate students in Evangelista's lab are developing algorithms to simulate quantum software so they can run tests and adapt the design based on the results.

Much of Evangelista’s work involves trying to predict the collective behavior of strongly correlated electrons. In order to understand how a drug interacts with a protein, for example, he needs to consider how it affects the hundreds of thousands of atoms in that protein, along with the millions of electrons within those atoms.

“The problem quickly explodes in complexity,” Evangelista says. “Computationally, it’s difficult to account for all the possible combinations of ways the electrons could be interacting. The computer soon runs out of memory.”

A classical computer stores memory in a line of “bits,” which are represented by either a “0” or a “1.” It operates on chunks of 64 bits of memory at a time, and each bit is either distinctly a 0 or a 1. If you add another bit to the line, you get just one more bit of memory.

A quantum computer stores memory in quantum bits, or qubits. A single qubit can be either a 0 or a 1 — or mostly a 0 and part of a 1 — or any other combination of the two. When you add a qubit to a quantum computer, it increases the memory by a factor of two. The fastest quantum computers now available contain around 70 qubits.

“Quantum computers are not just exponentially faster, they work in a radically different way from classical computers,” Evangelista says.

For instance, a classical computer can determine all the consequences of a chess move by working one at a time through the chain of possible next moves. A quantum computer, however, could potentially determine all these possible moves in one go, without having to work through each step.

While quantum computers are powerful, they are also somewhat delicate.

“They’re extremely sensitive,” Evangelista says. “They have to be kept at low temperatures to maintain their coherence. In a typical setup, you also need a second computer kept at very low temperatures to drive the quantum computer, otherwise the heat from the wires coming out will destroy entanglement.”

The potential error rate is one of the challenges of the DOE project to develop quantum software. The researchers need to determine the range of errors that can still yield a practical solution to a calculation. They will also develop standard benchmarks for testing the accuracy and computing power of new quantum hardware and they will validate prototypes of quantum computers in collaborations with industry partners Google and Rigetti.

Just as they develop algorithms to simulate chemical processes, Evangelista and his graduate students are now developing algorithms to simulate quantum software so they can run tests and adapt the design based on the results.

Evangelista pulled together researchers from other universities with a range of expertise for the project, including some who are new to quantum computing and others who are already experts in the field. The team includes scientists from Rice University, Northwestern, the University of Michigan, CalTech, the University of Toronto and Dartmouth.

The long-range goal is to spur the development of more efficient energy sources, including solar power, by providing detailed data on phenomena such as the ways electrons in a molecule are affected when that molecule absorbs light.

“Ultimately, such theoretical insights could provide a rational path to efforts like making solar cells more efficient, saving the time and money needed to conduct trial-and-error experiments in a lab,” Evangelista says.

Evangelista also has ongoing collaborations with Emory chemistry professor Tim Lian, studying ways to harvest and convert solar energy into chemical fuels. In 2017, Evangelista won the Dirac Medal, one of the world’s most prestigious awards for theoretical and computational chemists under 40.

Related:
$2 million NSF grant funds physicists' quest for optical transistors
Chemists find new way to do light-driven reactions
Physicists devise method to reveal how light affects materials

Monday, February 4, 2019

Take a 60-minute tour of space, time and spacetime



“I’ll begin with Saint Augustine,” says Emory physicist Erin Bonning, referring to the 4th-century philosopher and theologian who wrote some of the earliest known reflections on time and how humans perceive it. He summed time up: “I know well enough what it is, provided that nobody asks me; but if I am asked what it is, and try to explain, I am baffled.”

Bonning, director of the Emory Planetarium and a lecturer in the Department of Physics, collapses centuries of ideas and discovery about the universe into a mind-bending, 60-minute talk, “Space, Time and Spacetime,” that you can watch in the video above.

Bonning explains the ongoing quest for our understanding of time and how it relates to space: From recognition of the regular appearances of the sun, to the sense of time flowing through an hour glass, to the ticking of the first mechanical clocks, and on through the insights of Newton, Copernicus, Galileo, Michelson, Einstein and more. She even gives the perspective of aliens whizzing by Earth in a spaceship.

She winds up her talk, a recently delivered Emory Williams Lecture in the Liberal Arts, by discussing explorations of gravitational waves, dark matter and the drive to manipulate spacetime deliberately.

Related:
Fantastic light: From science fiction to fact

Wednesday, January 23, 2019

Growing knowledge and healthy food

Oxford student Gratia Sullivan unearths a bunch of radishes destined for the campus kitchens and community consumers. Photo by Kay Hinton.

From Emory Magazine

As an undergraduate biology major at Clemson University, Daniel Parson recognized the disconnect between environmental sustainability and traditional agriculture. He went on to get a masters degree in plant and environmental science from Clemson and spent more than a dozen years working in organic farming in Georgia and South Carolina.

"We look at nature as wilderness, but we also need things from nature and we need to learn how to get them without destroying it," says Parson.

He joined Emory's Oxford campus in 2014 to run the Oxford Organic Farm, an 11-acre piece of land that provides produce for the university's dining halls and farmers markets and unique learning opportunities for students.

"We try to match the seasons with when students are on campus so our work-student students who are here every day have the best experience possible and so we can work with faculty to connect course curriculum to the farm," says Parson, whose official title is farmer-educator. "For economics classes I might talk about how we set prices and interact with markets, but for other classes I may just be talking about the experiences I've had and how that connects with what they are discussing in class."

Click here to read more.

Wednesday, December 19, 2018

Chemical catalyst turns 'trash' to 'treasure'

Emory graduate student J.T. Fu, first author of the Nature paper, holds vials of the catalyst and the reagent used in the reaction.

By Carol Clark

For decades, chemists have aspired to do carefully controlled chemistry on carbon-hydrogen bonds. The challenge is staggering. It requires the power of a miniature wrecking ball to break these extremely strong bonds, combined with the finesse of microscopic tweezers to single out specific C-H bonds among the many crowded onto a molecule.

The journal Nature published a method that combines both these factors to make an inert C-H bond reactive — effectively turning chemical “trash” to “treasure.”

“We can change a cheap and abundant hydrocarbon with limited usefulness into a valuable scaffold for developing new compounds — such as pharmaceuticals and other fine chemicals,” says J.T. Fu, a graduate student at Emory University and first author of the paper.

The Nature paper is the latest in a series from Emory University demonstrating the ability to use a dirhodium catalyst to selectively functionalize C-H bonds in a streamlined manner, while also maintaining virtually full control of the three-dimensional shape of the molecules produced.

“This latest catalyst is so selective that it goes cleanly for just one C-H bond — even though there are several C-H bonds very similar to it within the molecule,” says Huw Davies, Emory professor of organic chemistry and senior author of the paper. “That was a huge surprise, even to us.”

Click here to read more about the discovery.

Related:
Creating global bonds
C-H center nets $20 million
A huge shortcut for synthesis